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KMID : 0438420100170020055
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Korean Journal of Bone Metabolism
2010 Volume.17 No. 2 p.55 ~ p.62
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Atypical Subtrochanteric and Diaphyseal Fractures of the Femur Possibly Associated with Bisphosphonate
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Seo Jun-Young
Nam Kwang-Woo
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Abstract
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Several recent papers have reported atypical femoral subtrochanteric or dyaphyseal insufficiency fractures associated
with long-term bisphosphonate use. There still has been the debate on the relationship between bisphosphonates and
atypical fractures. Furthermore, the pathogenesis of the atypical femoral fractures is not fully elucidated. Here, we
intended to look into the atypical femoral subtrochanteric or dyaphyseal fracture through the literature search and also
discuss the natural course of the femoral insufficiency fracture. We found that atypical femoral fractures have somewhat
a relation with bisphosphonates despite rare occurrence. We also found that atypical cortical reactions or incomplete
atypical fractures are ultimately apt to fracture completely. Conclusively it is better to perform prophylactic stabilization
in the atypical femoral subtrochanteric or dyaphyseal fractures if pain, the longer duration of bisphosphonate use, or
the cortical thickening on outer cortex is present.
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KEYWORD
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Atypical, Bisphosphonate, Femur, Insufficiency fracture, Subtrochanter
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